Supplements
The latest from Supplements on Vitalspell.

Fish oil supplements face mounting evidence of limited benefits and real risks
A growing body of research suggests fish oil supplements may not deliver the broad health benefits consumers expect and could pose risks including increased atrial fibrillation and possible cognitive decline in older adults.

Brain health supplements: what the evidence says about what works
Brain health supplements are a multibillion-dollar market built on promises most products cannot back. Only multivitamins and creatine have consistent trial data, while most other products sell on claims the research simply does not support.

Akkermansia muciniphila: what the evidence actually says about the internet's favorite probiotic
Akkermansia muciniphila has attracted more supplement-industry attention than any microbe since Lactobacillus. Here is what the human trials actually show about weight loss, blood sugar, gut barrier repair, and the other claims being made.

Vitamin B12 and muscle mitochondria: what the latest research reveals
New research from Cornell shows vitamin B12 directly affects skeletal muscle energy production at the mitochondrial level. In aged mice, B12 supplementation doubled a key enzyme's activity, raising questions about whether marginal deficiency contributes to age-related muscle decline.

Magnesium and sleep: what the evidence says about the most recommended bedtime supplement
Magnesium has a plausible mechanism for improving sleep through GABA and NMDA receptors, but the trial data shows the effect is modest and largely limited to people with low dietary magnesium intake.
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NMN and NR supplements: what the evidence says about NAD precursors and aging
NAD levels drop by roughly half between age 40 and 70, and supplement companies are selling NMN and NR as the solution. The human trials show measurable NAD increases but inconsistent clinical benefits, and the regulatory situation for NMN remains unsettled.

Creatine monohydrate: what the evidence says about the most studied supplement in sports
Creatine monohydrate is the most studied sports supplement in history. It works reliably for strength and power, shows emerging promise for brain health, and costs pennies per gram. Here is why the more expensive forms have almost no evidence of superiority.